Treatment Outcome in Polycystic Ovarian Syndrome-Related Infertility
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Treatment Outcome in Polycystic Ovarian Syndrome-Related Infertility. (2024). The Maldives National Journal of Research, 12(Special Issue), 22-36. https://doi.org/10.62338/xv17n958

Abstract

The declining fertility rate has been observed in the past few decades in Maldives. One of the most prevalent diseases that cause this complication is polycystic ovarian syndrome (PCOS). PCOS is a hormonal condition that has affected 13% of women in the reproductive age group globally. This is a chronic condition where various treatment options have been used to counter the complication. In this study, we analyze the effectiveness of one of the most common treatment regimens available in Maldives, letrozole, and letrozole combined with gonadotropins, for women with PCOS-related infertility.This quantitative, retrospective study analyzes data from 2019 to 2024. The population consists of women who received treatment for infertility due to PCOS at Indira Gandhi Memorial Hospital and My Clinic Private Limited, between January 1, 2019, and December 31, 2023. Our total study sample was 173 patients.Using the logistic regression model, we observed that, when compared with those who were more than 35 years, patients who were less than 25 years old, had a 9.5 times more likelihood of getting pregnant. After excluding the other variables, the odds ratio for ages less than 25 years increased from 9.5 to 13.3. Furthermore, patients who are 26 to 30 years of age show a significantly higher successful outcome when other variables are adjusted. This study shows that there is a significant relationship between age and treatment outcome of PCOS-related infertility.

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References

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